HSP70 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.3HG0302810 (symbol HSP70) on barley chromosome 3H encodes an ATP-dependent protein folding chaperone belonging to the Hsp70 family, with ATP hydrolase activity and heat shock protein binding capacity. The gene is associated with protein folding in the endoplasmic reticulum, protein refolding, the ERAD pathway, and the unfolded protein response. It is linked to stress responses including heat, virus, and immune responses, as well as innate immunity, pollen tube growth, and lipid metabolism. The encoded protein localises to the ER chaperone complex, ER lumen, chloroplast membrane, tonoplast, cytoplasm, and nucleus. Studies of related genes in other species link the family to spikelet number and heat and cold tolerance.