SHM4 — Glycine max

Summary

GmSHM4 (GLYMA_08G108900V4) on soybean chromosome 8 encodes a serine hydroxymethyltransferase, an enzyme with glycine hydroxymethyltransferase activity that also binds pyridoxal phosphate and salicylic acid. The gene is associated with one-carbon metabolism, tetrahydrofolate interconversion, folate metabolism, and polyamine biosynthesis and response. It has been linked to responses to flooding, salinity, nematodes, and misfolded proteins, as well as to virus-induced post-transcriptional gene silencing and deubiquitination. Associations with agronomic traits include stearic acid content, seed coat color, herbicide sensitivity, salt tolerance, cadmium tolerance, disease tolerance, and root and meristem development traits. The protein localizes to mitochondria, the cytosol, the nucleus, the plasmalemma, and plasmodesmata. Related genes in other species link the family to photorespiration and zinc deficiency tolerance.

Annotations

Chromosome
8
Related genes
SHM4, UBP16, RPT2A
GO terms
homeostasis, Circadian Rhythm, Leaf Development, Pyridoxal Phosphate Binding, heme anabolism, Homologous Recombination, Leaf Morphogenesis, Flower Development
Publications
17825468, 33961777, 32502259, 21378116, 28695315, 16336779, PMID:17227551, 16719932
Traits
photorespiration, inflorescence architecture, Severe Narrow Leaves, Small Flowers, Aborted Siliques, Dwarf Plants, Short Roots, Narrow Serrated Leaves, Early Flowering, Reduced Fertility, Narrow Rosette Leaves, Small Flowers, Aborted Siliques, Dwarf Plants, Proteasome Defects, Shorter Roots, Altered Stress Response, Large Plants, Narrow Serrated Leaves, MG132 Hyposensitivity, Milder Root and Shoot Meristem Defects