JHS1 — Daucus carota subsp. sativus

Summary

DcJHS1 (DCAR_029534) on carrot chromosome 9 encodes a protein with DNA helicase and ssDNA-dependent ATPase activities, containing Dna2/JHS1_DEXXQ-box, Cas4_exonuclease, and P-loop NTPase domains. It is associated with DNA replication, repair, and damage response, as well as endocytosis, exocytosis, cytokinesis, cell division, and embryo development through seed dormancy. The protein localizes to the nucleus and is linked to cell cycle pathways including S phase and mitosis. Related genes in other species are linked to meristem identity, cell cycle trait, DNA damage repair, enlarged shoot apical meristem, fasciation, disorganized root cell files, meristem maintenance, embryo lethality at preglobular stage, embryo defect at globular stage, and cell cycle regulation.