PRP8 — Daucus carota subsp. sativus

Summary

DCAR_025515 (DcPRP8) on carrot chromosome 7 encodes an MPN domain-containing protein with multiple RNA-binding domains characteristic of the spliceosomal Prp8 family. The gene product is associated with pre-mRNA splicing, spliceosomal complex assembly, and mRNA 3'-splice site recognition, and localises to U5 snRNP and catalytic step 2 spliceosome components. In carrot, DcPRP8 has been linked to sucrose and soluble sugar content. The gene is also associated with a wide range of traits including yield, flowering time, seed longevity, bacterial blight disease resistance, boron sensitivity, cellulose content, and responses to high and low temperature stress. Studies of related genes in other species connect the family to pre-mRNA splicing, circadian rhythm regulation, pathogen resistance, and root elongation.