HPR3 — Daucus carota subsp. sativus

Summary

DCAR_025130 (symbol HPR3, DcHPR3) on carrot chromosome 7 encodes a protein with a D-isomer-specific 2-hydroxyacid dehydrogenase catalytic domain and NAD(P)-binding domain, annotated with multiple oxidoreductase activities including glyoxylate reductase (NADH), hydroxypyruvate reductase (NADPH), glycerate dehydrogenase, and formate dehydrogenase activities. The gene is associated with photorespiration, the oxidative photosynthetic carbon pathway, formate breakdown, fatty acid oxidation and anabolism, lipid and glucose metabolism, and fat cell differentiation. Its product localizes to mitochondria and cytosol. Studies of related genes in other species link the HPR3 family to carotenoid and flavonoid content.