GR — Cucumis sativus

Summary

CSA_7G378460, designated GR (synonyms CsGR2, GR2, CsGOR, CsGR-RBP3), encodes a glutathione reductase (EC 1.8.1.7) on cucumber chromosome 7. The product possesses FAD/NAD-binding and pyridine nucleotide-disulfide oxidoreductase domains and exhibits glutathione reductase, thioredoxin reductase, leghemoglobin reductase, and dihydrolipoyl dehydrogenase activities, along with NADP, FAD, copper, and metal binding. GR is associated with the ascorbate-glutathione cycle, cellular redox homeostasis, cold acclimation, 2-oxoglutarate metabolism, glycine decarboxylation, mitochondrial protein import, and chlorophyll fluorescence. It localizes to mitochondria, chloroplast stroma, and the glycine cleavage system. The gene is linked to traits including net photosynthetic rate, transpiration rate, chlorophyll content, plant height, stem diameter, root length, stomatal resistance, ethylene sensitivity, and tolerance to oxidative, low-temperature, manganese, and phenanthrene stress. Studies of related genes in other species connect the family to embryo development, leaf senescence, stomatal aperture, drought response, and glutathione redox homeostasis.