AFB1 — Cucumis sativus

Summary

CsAFB1 (CSA_7G393970) on cucumber chromosome 7 encodes Transport Inhibitor Response 1, an F-box protein with leucine-rich repeats that exhibits auxin receptor activity, NEDD8 transferase activity, ubiquitin-like protein transferase activity, and auxin influx/efflux transmembrane transporter activities. The gene is associated with auxin signalling, SCF complex assembly, regulation of protein-nucleus import, establishment of planar polarity, and cellular responses to nitrate and cyclopentenone. It localises to the nuclear SCF complex and ubiquitin ligase complex. CsAFB1 is associated with seedling vigour, biomass yield, seed yield, fruit growth and development, adventitious root number, phototropism, temperature stress response, aluminium response, herbicide sensitivity, leaf morphogenesis, root system architecture, and vascular patterning. Studies of related genes in other species link the gene to primary root length, lateral root formation, hypocotyl hook development, leaf flattening, and biomass production.