MLO — Cucumis sativus

Summary

CSA_6G518200, designated MLO (also known as MLO2, MLO6, MLO12, CsPMR2, and CsMLO), encodes a calmodulin-binding protein localized to the membrane, plasmodesma, Golgi complex, and extracellular space. In cucumber, this gene is associated with defense responses to fungi and bacteria, immune response, signal transduction, cell wall thickening, calcium signaling, ABA signaling, and downregulation of defense response. It has been linked to Botrytis cinerea resistance, leaf senescence, callose deposition, and systemic acquired resistance. Studies of related genes in other species connect the family to powdery mildew resistance and susceptibility, bacterial wilt susceptibility, heat tolerance, ozone tolerance, and disease resistance or susceptibility, as well as traits including water use efficiency, seed maturation, stomatal resistance, and high temperature stress response.