GOX — Cucumis sativus

Summary

CsGOX (CSA_6G523470) in cucumber encodes an (S)-2-hydroxy-acid oxidase (EC 1.1.3.15), a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family, and also exhibits RNA folding chaperone, DNA-binding transcription factor activity, and cis-regulatory region sequence-specific DNA binding. The gene is associated with glycolate metabolism, the oxidative photosynthetic carbon pathway, glyoxylate cycle, hydrogen peroxide biosynthesis, and regulation of photosynthesis. It is linked to total soluble sugar content, fruit quality, biomass yield, net photosynthetic rate, seed size, flowering time, leaf senescence, root development, and responses to high and low temperature stress, drought, and salt stress. Localization evidence connects CsGOX to chloroplast stroma, mitochondria, cytosol, apoplast, and stress granules. Studies of related genes in other species link the family to photorespiration, oxidative stress tolerance, and disease resistance.