BI1 — Cucumis sativus

Summary

CSA_3G912940 (BI1, CsBI-1) on cucumber chromosome 3 encodes a Bax inhibitor 1-like protein, a member of the Bax inhibitor-1 family, with protease binding, calcium channel activity, oxidoreductase activity, and proton-transporting ATPase activity. In cucumber, BI1 is associated with fruit bitterness, fruit development, response to insects, UV response, calcium signaling, lipid and very-long-chain fatty acid metabolism, glucosinolate anabolism, and downregulation of programmed cell death. It localizes to the endoplasmic reticulum, vacuolar membrane, Golgi, chloroplast envelope, and nuclear envelope. The gene is linked to traits including fruit bitterness, mineral and ion transport, alkali soil sensitivity, cadmium concentration, water use efficiency, and responses to downy mildew, powdery mildew, aluminum, and low temperature stress. Studies of related genes in other species connect the family to cell death suppression, endoplasmic reticulum stress tolerance, and cold, drought, and salt stress tolerance.