HA1 — Cucumis sativus

Summary

CsHA1 (CSA_4G006220) in cucumber encodes a P-type ATPase (EC 7.1.2.1) with cation-transporting, proton-transporting, and P-type ATPase activities, along with additional annotated molecular functions including transmembrane signaling receptor, guanylyl cyclase, and peptide receptor activities. The gene is associated with proton export across the plasma membrane, vacuolar acidification, cell pH regulation, nitrate import, and very-long-chain fatty acid metabolism. It has been linked to numerous agronomically relevant traits including alkali soil sensitivity, manganese sensitivity, iron content, root volume, plant dry weight, water stress response, bacterial disease response, brassinosteroid and auxin sensitivity, high temperature stress response, and stamen and pistil morphology. Localization evidence connects the product to the plasma membrane, tonoplast, ER, and plant-type vacuole. Studies of related genes in other species link the gene family to root hair development, pollen tube growth, salt resistance, drought response, stomatal movement, and pathogen defense.