HA1 — Cucumis sativus

Summary

CsHA1 (CSA_1G045600) on cucumber chromosome 1 encodes a P-type ATPase with cation-transporting ATPase activity, proton-transporting ATPase activity, and additional annotated molecular functions including guanylyl cyclase, phosphatase, and calmodulin-binding activities. The gene is associated with proton export across the plasma membrane, vacuolar acidification, cell pH regulation, nitrate import, and very-long-chain fatty acid metabolism. It has been linked to numerous agronomically relevant traits including alkali soil sensitivity, manganese sensitivity, iron content, water stress response, bacterial disease response, photosynthetic rate, root hair formation and elongation, plant height, growth rate, salt resistance, drought response, and anther development. Localization evidence connects the product to the plasma membrane, tonoplast, ER membrane, and plant-type vacuole. Studies of related genes in other species link this gene family to cell elongation, pathogen defense, pollen tube growth, and hydrotropic response.