ICS1 — Cucumis sativus

Summary

CSA_1G008580 (ICS1, also known as SID2, EDS16, or CsICS2) on cucumber chromosome 1 encodes an isochorismate synthase with isochorismate mutase and anthranilate synthase activities, belonging to the MenF-like and IsoChor_synthase families. The gene is associated with salicylic acid biosynthesis and signaling, systemic acquired resistance, immunity, and defense responses to bacteria and fungal colonization. It is linked to leaf abscission, stomatal movement, photosynthesis, calcium signaling, phylloquinone and tryptophan formation, and lipid metabolism. The encoded protein localizes to the plastid and the anthranilate synthase complex. Associations also include root development, lateral root number, ozone sensitivity, herbicide tolerance, and responses to high light, sulfur limitation, and insect egg deposition. Studies of related genes in other species link the family to salicylic acid accumulation, powdery mildew resistance, cold tolerance, and heat and drought tolerance.