PRP8 — Cucumis melo

Summary

MELO3C023427.2 (CmPRP8) on melon chromosome 2 encodes a spliceosomal protein with multiple RNA-binding domains, including Prp8_U5-snRNA-bd and RRM_spliceosomal_PrP8 domains, and is annotated with pre-mRNA intron binding, U1, U2, U5, and U6 snRNA binding, as well as protein methylase, metallopeptidase, helicase, and ubiquitin ligase activities. The gene is associated with mRNA splicing, spliceosomal complex assembly, miRNA metabolic processes, and posttranscriptional gene silencing. It is linked to a wide range of agronomic traits, including fruit sweetness, fruit weight and size, yield, stem length and diameter, bacterial blight disease resistance, heterosis, cellulose content, seed longevity, flowering time, and responses to high and low temperature stress, boron sensitivity, and nitrate uptake. The protein localizes to spliceosomal complexes, nuclear speckles, and the ESCRT III complex.