ASD — Cucumis melo

Summary

MELO3C023620.2, designated CmASD on melon chromosome 2, encodes a short-chain dehydrogenase/reductase (SDR) family protein with NAD(P)-binding domain. The product exhibits multiple dehydrogenase activities, including carveol, isopiperitenol, momilactone-A synthase, zerumbone synthase, borneol, secoisolariciresinol and xanthoxin dehydrogenase activities, as well as oxidoreductase and isomerase activities. CmASD is associated with the biosynthesis of menthol, camphor, lignans, monoterpenoids, abscisic acid, phenylpropanoids and amino acids, and with the shikimate pathway. It is linked to responses to UV, jasmonic acid and wounding, and to protein homotetramerization. The protein localises to mitochondria and the cytosol. Studies of related genes in other species connect the family to additional dehydrogenase activities.