N — Cucumis melo

Summary

MELO3C022145.2 (symbol CmBWS1) on melon chromosome 10 encodes a protein with TIR, NB-ARC and LRR domains, and possesses NADP nucleosidase, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, ATP hydrolase and DNA-binding transcription factor activities. The gene is associated with defence responses to bacteria, fungi and viruses, positive regulation of the hypersensitive response and programmed cell death, brassinosteroid-mediated signalling, response to cold, and regulation of transcription. It has been linked to traits including nitrate uptake, leaf composition, seedling growth and organ identity, and to phenotypes such as chilling tolerance, freezing tolerance, dwarfism, curly leaves, accelerated senescence, disease resistance (including to Pseudomonas syringae, Ralstonia solanacearum and Colletotrichum higginsianum), bacterial wilt tolerance, fruit wart formation, and lethal systemic necrosis. The protein localises to the nucleus, cytosol, membrane, endomembrane system, chloroplast envelope, Golgi, mitochondria and plant-type vacuole.