M2 — Cucumis melo

Summary

MELO3C022335.2 (CmM2) on melon chromosome 12 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with cis-trans proline isomerase activity, and is also annotated for GTP:GDP antiporter, L-serine O-acetyltransferase, peroxidase, salicylic acid, cyclosporin A, histone, and chromatin binding activities. The gene is associated with diverse biological processes including protein proline isomerization, chaperone-mediated protein complex assembly, regulation of ARF protein signal transduction, alternative mRNA splicing, basipetal auxin transport, response to light intensity and chlorate, and cysteine anabolism. It localizes to the Golgi stack, thylakoid lumen, secretory vesicle, and proteasome. Associations with agronomic traits include variegated leaf, starch grain synthesis, respiration rate, photosynthetic rate, sucrose content, herbicide sensitivity, root hair length, root mass density, jasmonic acid content, heat stress tolerance, and disease resistance. Studies of related genes in other species link the family to hydrotropism, phototropism, cold stress tolerance, drought response, and embryo patterning.