HMG1 — Cucumis melo

Summary

MELO3C015691.2 (HMG1) in melon (Cucumis melo) encodes a hydroxymethylglutaryl-CoA reductase (NADPH) (EC 1.1.1.34). The protein contains HMG-CoA reductase domains and is associated with multiple membrane locations including the ER, plastid, mitochondrial and peroxisomal membranes. Annotated biological processes include the mevalonate pathway, sterol, triterpenoid, isoprenoid and saponin biosynthesis, CoA metabolism, fruit ripening, response to jasmonic acid, and cell division. The gene is associated with fruit size, photosynthetic rate, plant height, biomass, flower morphology and color, flowering time, male fertility, senescence, seed phytosterol content, and responses to pathogens, wounding, herbivores and light. Studies of related genes in other species connect the family to fruit development, isoprenoid and steroidal glycoalkaloid content, disease resistance, and root elongation inhibition.