MLO — Cucumis melo

Summary

MELO3C012438.2 (MLO) on melon chromosome 11 encodes a calmodulin-binding membrane protein. The gene is associated with powdery mildew susceptibility in melon, and with downregulation of defense response, defense response to fungi and bacteria, and response to fungi. It has been connected to Botrytis cinerea resistance, leaf senescence, callose deposition, and systemic acquired resistance. The MLO protein localises to the plasmalemma, Golgi complex, plasmodesma, mitochondria, and extracellular. Related genes in other species are linked to powdery mildew resistance, disease resistance and susceptibility, ozone tolerance, non-host resistance to Magnaporthe oryzae, bacterial wilt susceptibility, bacterial resistance, and heat tolerance.