LOC101493700 — Cicer arietinum

Summary

LOC101493700 on chickpea chromosome 2 encodes a protein with NADP nucleosidase and DPNase activities, belonging to the WHD_ROQ1-like, TIR, NB-ARC, and LRR domain families characteristic of plant disease resistance proteins. The gene is associated with NAD breakdown, upregulation of programmed cell death, the hypersensitive response, and defense responses to other organisms including fungi and viruses. Its product localizes to the plasma membrane, cytoplasm, and nucleus, and binds ADP, ATP, and exhibits protein homodimerization activity. Studies of related genes in other species link the family to ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase activity and RNase H-like domains, though these associations are not yet established in chickpea.