LOC101493855 — Cicer arietinum

Summary

LOC101493855 on chickpea chromosome 5 encodes a protein with an aldo-keto reductase domain (AKR4A/B family) and exhibits 6'-deoxychalcone synthase, 3''-deamino-3''-oxonicotianamine reductase, and aldose reductase (NADPH) activities, and oxidoreductase activity acting on CH-OH group donors with NAD or NADP as acceptor. This gene is associated with secondary metabolite biosynthesis, including flavonoid and alkaloid anabolism, as well as siderophore anabolism, and is linked to cellular responses to zinc and iron ion starvation, stress responses, and homeostasis. The encoded protein localizes to the cytosol. Studies of related genes in other species connect the family to further oxidoreductase activities (EC 2.3.1.170, 1.1.1.285).

Annotations

Chromosome
5
Related genes
COR2, GLYMA_18G285800V4, PHAVU_008G015800, LOC101500008, LOC101493536
GO terms
homeostasis, flavonoid anabolism, alkaloid anabolism, Response To Iron Ion Starvation, Cytosol, Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor, 6'-deoxychalcone Synthase Activity, Aldose Reductase (NADPH) Activity
Publications
25068786, PMID:18089549, PMID:24280374, PMID:21320317, PMID:29979476, PMID:28798320, PMID:26224556, PMID:10417697