ICDH — Capsicum annuum

Summary

CaICDH (T459_30272) on pepper chromosome 12 encodes a protein containing the Isocitrate_DH_NADP and IsoPropMal-DH-like domains. It exhibits NADP isocitric dehydrogenase, NAD binding, and metal-binding activities. The gene is associated with the TCA cycle, glyoxylate cycle, cellular respiration, NADP metabolism, and isocitrate metabolism. It has been linked to fruit ripening, microsporogenesis, cell growth and death, brassinosteroid-mediated signalling, defence response to bacteria, and detoxification. Associations with agronomic traits include pungency, cytoplasmic male sterility, respiration rate, photosynthetic rate, and root morphology. The encoded protein localises to multiple compartments including chloroplast thylakoid and stroma, plastid, mitochondria, cytosol, plasmalemma, apoplast, and plasmodesmata. Studies of related genes in other species link the family to seed weight, drought tolerance, salt response, chlorophyll content, and disease tolerance.