PGD1 — Capsicum annuum

Summary

CaPGD1 (T459_30581) on pepper chromosome 12 encodes a 6-phosphogluconate dehydrogenase (EC 1.1.1.44) that also possesses protein kinase activity and binds NADP, ATP, calcium/calmodulin, and phosphorylated amino acids. The gene is associated with diverse biological processes including fruit ripening, cellular respiration, D-gluconate metabolism, regulation of pollen tube growth, responses to cold, sugars, and abscisic acid, as well as brassinosteroid-mediated signaling and cell death. It is linked to traits such as pungency, manganese sensitivity, stomatal opening and closure, root thickness, salt tolerance, disease tolerance, and abscisic acid sensitivity. The encoded protein localizes to multiple cellular compartments including the cytosol, plastid, mitochondria, apoplast, and plasmodesmata. Studies of related genes in other species connect the family to root growth, chlorophyll content, and nitrate uptake.