ICDH — Capsicum annuum

Summary

CaICDH (T459_29283) on pepper chromosome 12 encodes an NADP-dependent isocitrate dehydrogenase (EC 1.1.1.42) with isocitrate/isopropylmalate dehydrogenase domains and activities including NADP isocitric dehydrogenase, NAD binding, and metal binding. The gene is associated with the TCA cycle, glyoxylate cycle, cellular respiration, NAD(P) metabolism, fruit ripening, microsporogenesis, cell growth and death, brassinosteroid-mediated signalling, defence response to bacteria, and response to zinc. It has been linked to pungency, cytoplasmic male sterility, photosynthetic and respiration rates, root morphology, nitrogen metabolism, redox homeostasis, and hydraulic conductivity. The protein localises to chloroplasts (thylakoid and stroma), mitochondria, plastids, cytosol, plasmalemma, apoplast, and plasmodesmata. Studies of related genes in other species connect the family to seed weight, drought and salt tolerance, disease tolerance, and chlorophyll content.