ICDH — Capsicum annuum

Summary

CaICDH (T459_29244) on pepper chromosome 12 encodes an NADP-dependent isocitrate dehydrogenase, an enzyme with NADP isocitric dehydrogenase activity that also binds NAD, ATP, copper, magnesium, and metals. The gene is associated with the TCA cycle, glyoxylate cycle, cellular respiration, NADP and isocitrate metabolism, detoxification, fruit ripening, microsporogenesis, cell growth and death, brassinosteroid-mediated signalling, and defence response to bacteria. It has been connected to pungency, cytoplasmic male sterility, respiration and photosynthetic rates, root morphology, nitrogen metabolism, histone methylation, redox homeostasis, and hydraulic conductivity. The protein localises to chloroplast thylakoid and stroma, plastid, mitochondria, cytosol, plasmalemma, apoplast, and plasmodesmata. Studies of related genes in other species link the family to seed weight, chlorophyll content, drought and salt tolerance, disease tolerance, and starch, sugar, and protein content.