ICDH — Capsicum annuum

Summary

CaICDH (T459_08886) on pepper chromosome 3 encodes an NADP-isocitrate dehydrogenase with NADP isocitric dehydrogenase and NAD isocitric dehydrogenase activities, binding NAD, ATP, metals including magnesium and copper, and exhibiting protein homodimerization activity. The gene is associated with the TCA cycle, glyoxylate cycle, cellular respiration, NAD and NADP metabolism, isocitrate metabolism, detoxification, fruit ripening, microsporogenesis, cell growth and death, brassinosteroid-mediated signalling, and defence response to bacteria. It has been linked to pungency, cytoplasmic male sterility, respiration rate, photosynthetic rate, root morphology, nitrogen metabolism, histone methylation, redox homeostasis, and hydraulic conductivity. The product localises to chloroplast thylakoid and stroma, plastid, mitochondria, cytosol, apoplast, plasmodesma, and plasmalemma. Studies of related genes in other species connect the family to traits including seed weight, drought tolerance, salt response, chlorophyll content, and disease tolerance.