HMA2 — Camelina sativa
Summary
CsHMA3 (CSA10G012420, also known as HMA2) encodes a P-type ATPase of the IB subfamily, a cation-transporting ATPase with activity toward divalent and monovalent copper, zinc, cadmium, and calcium, and is localized to the vacuolar and Golgi membranes as well as the plasmalemma. In Camelina sativa, this gene is associated with detoxification of cadmium and copper ions, copper ion homeostasis, membrane transport, and defense responses to bacteria, including detection of bacteria and hypersensitive cell death. It has also been linked to leaf width and shape, bacterial disease response, and disease tolerance. Studies of related genes in other species connect the family to cadmium detoxification, zinc homeostasis, shoot cadmium concentration, leaf cadmium accumulation, and lead tolerance, as well as to bacterial defense and effector-triggered immunity.
Annotations
- Chromosome
- 10
- Related genes
- HMA3, HMA2, RPS2
- GO terms
- Response To Toxic Substance, P-type ATPase activity, Detoxification Of Copper Ion, ADP Binding, plasmalemma, response to thirst, P-type Monovalent Copper Transporter Activity, metal binding
- Publications
- 30300945, 24377444, 16608451, 17447913, 22880057, 31362467, 17181774, 31550400
- Traits
- disease resistance, cadmium transport, cadmium tolerance, hypersensitive cell death response, other miscellaneous trait, Susceptible to Pseudomonas with avrRpt2, Lacks Hypersensitive Response, Impaired RPM1-Mediated Resistance to Bacterial Effectors, Susceptible to Pseudomonas with avrRpm1, avrB, or avrRpt2