SS2 — Camelina sativa

Summary

CsERG9 (CSA10G007480, also known as SS2, SQS1, CsSQS1, and ERG9) on Camelina sativa chromosome 10 encodes a squalene synthase with EC 2.5.1.21 activity, belonging to the squalene/phytoene synthase family. The enzyme is associated with squalene synthase activity, metal binding, and D-glucose transmembrane transporter activity, and is linked to farnesyl diphosphate metabolism, sterol, triterpenoid, saponin, and isoprenoid anabolism, as well as lipogenesis. It has been connected to responses to nitric oxide, hydrogen peroxide, salicylate, ethylene, jasmonic acid, vanadate, and fungal molecules. The protein localises to the ER membrane, mitochondria, and plasmalemma. The gene is associated with triterpenoid production. Studies of related genes in other species link the family to triterpene, brassinosteroid, and sterol biosynthesis, and to traits including brassinosteroid and carotenoid content, water use efficiency, and drought tolerance.