CCT3 — Camelina sativa

Summary

CsCCT3 (CSA08G024240) on Camelina sativa chromosome 8 encodes a chaperonin containing TCP-1 subunit gamma, a component of the GroEL-like chaperonin family with ATP-dependent protein folding chaperone activity and ATP hydrolase activity. This gene is associated with protein folding and refolding, heat acclimation, inflorescence development, protein-peroxisome targeting, and upregulation of transport. It localizes to the cytosol, nucleus, plastid, plasmodesma, TriC complex, and Cul4-RING E3 ubiquitin ligase complex. CsCCT3 has been connected to selenium and sulfur content, leaf temperature, proteotoxic stress tolerance, peroxisome function, and PTS2 protein import into peroxisomes. Studies of related genes in other species link the family to nitric oxide production, cadmium tolerance, glyoxysomal function, and PTS1 protein import into peroxisomes.