PDE1 — Camelina sativa

Summary

CsPDE1 (CSA04G063680) on Camelina sativa chromosome 4 encodes a protein with NAD(P)-binding and D-isomer-specific 2-hydroxyacid dehydrogenase domains that exhibits multiple oxidoreductase activities, including formate dehydrogenase (NAD+), hydroxypyruvate reductase [NAD(P)H], glyoxylate reductase (NADH and NADPH), glycerate dehydrogenase (NAD+), and D-lactate dehydrogenase (NAD+). The gene is associated with photorespiration, the oxidative photosynthetic carbon pathway, formate breakdown, immune response, hypersensitivity, and negative regulation of cellular response to phosphate starvation. Its product localizes to mitochondria and cytosol. CsPDE1 is associated with phosphate-deficiency tolerance. Studies of related genes in other species link the family to additional hydroxypyruvate and formate metabolism functions.