PDE1 — Camelina sativa

Summary

CsPDE1 (CSA05G003670) on Camelina sativa chromosome 5 encodes a D-isomer-specific 2-hydroxyacid dehydrogenase with NAD(P)-binding and catalytic domains, annotated with multiple oxidoreductase activities including formate dehydrogenase (NAD+), (2R)-hydroxyphenylpyruvate reductase [NAD(P)H], hydroxypyruvate reductase [NAD(P)H], and glyoxylate reductase activities. The gene is associated with photorespiration, the oxidative photosynthetic carbon pathway, formate breakdown, and negative regulation of cellular response to phosphate starvation. It has been linked to phosphate-deficiency tolerance and to immune response, hypersensitivity, and homeostasis. The encoded protein localises to mitochondria and cytosol. Related genes in other species connect the family to additional hydroxyphenylpyruvate reductase and formate dehydrogenase activities.