CYP — Camelina sativa

Summary

CsCYP18-1 (CSA03G001300) on Camelina sativa chromosome 3 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with EC 5.2.1.8 activity, belonging to the Cyclophilin_A-like family. The gene product is associated with U5 and U2 snRNA binding, cyclosporin A binding, and protein binding, and is linked to mRNA splicing via the spliceosome, protein folding, and regulation of protein refolding. It has been connected to responses to abscisic acid, salt, mannitol, and heat, as well as detoxification and activation of salinity response. Localisation evidence places the protein in the nucleus, cytosol, cytoplasm, chloroplast stroma, nucleolus, stress granules, catalytic step 2 spliceosome, and plasmalemma. Related genes in other species link the cyclophilin family to high temperature stress response.