PAD3 — Camelina sativa

Summary

CsPAD3 (CSA03G016900) on Camelina sativa chromosome 3 encodes a cytochrome P450 family protein with dihydrocamalexic acid decarboxylase, costunolide synthase, and 4-hydroxyphenylacetaldehyde oxime monooxygenase activities. The gene is associated with indole phytoalexin, dhurrin, camalexin, alkaloid, and sesquiterpene biosynthetic processes, as well as regulation of systemic acquired resistance, response to insect, fruit ripening, response to bacteria, response to thirst, defence response to fungi, response to abscisic acid, and defense response. It is linked to aphid resistance, resistance to Leptosphaeria maculans, immunity, pathogen resistance, hypersensitive response, downy mildew resistance, powdery mildew resistance, induced systemic resistance against Botrytis cinerea, phytoalexin production, zinc stress tolerance, stress response, gene expression, resistance to Alternaria brassicicola, resistance to fungal pathogen, camalexin synthesis, phytoalexin biosynthesis, clubroot resistance, and disease resistance to Phytophthora brassicae. The encoded protein localizes to the endoplasmic reticulum membrane and lumen, as well as plasmodesmata, intracellular membrane-bounded organelle, and extracellular regions. Studies of related genes in other species further connect the family to camalexin accumulation and resistance to Botrytis cin