MBD7 — Brassica oleracea var. botrytis

Summary

BoMBD7, encoded by the gene BOLND125_C09P055870.1 on cauliflower chromosome 9, is a methyl-CpG-binding domain protein with annotated PRMT activity, histone acetyltransferase activity, and double-stranded methylated DNA binding. It localises to the nucleus, chromocenter, cytoplasm, and plasmodesma. The gene is associated with DNA methylation and demethylation, RNA-directed DNA methylation (RdDM), chromatin remodelling, and transcriptional gene silencing. It has been linked to epigenetic silencing, higher DNA methylation levels, and decreased tolerance to osmotic stress and ABA. Associations with root morphology traits have also been noted. Related genes in other species connect the family to methylated DNA binding, chromatin structure, and DNA methylation-induced gene silencing, and to hypermethylated DMRs and long roots on sucrose media.