SR1 — Brassica oleracea var. botrytis

Summary

BoSR1, encoded by gene BOLND125_C06P030730.1 on cauliflower chromosome 6, is a ZNF598/HEL2 family protein containing RING-HC, C2H2 zinc-finger and PAH domains. The product possesses ubiquitin ligase activity, binds ribosomes, mRNA, transcription cis-regulatory regions and proteins, and localises to the nucleus. In cauliflower, BoSR1 is associated with response to flooding, rescue of stalled cytosolic ribosomes, and protein ubiquitination. The gene has also been linked to increased oxidative stress sensitivity. Studies of related genes in other species connect the family to enhanced submergence tolerance.