PEUP2 — Brassica oleracea var. botrytis

Summary

BoPEUP2, also known as PEUP2 or BoATG18A, encodes a PROPPIN family protein containing WD40 repeats and is annotated with protein binding activity. The gene is associated with the regulation of autophagy, including its positive regulation, as well as nuclear export, response to starvation, leaf senescence, osmotic and salinity responses, oxidative stress, and defence response to fungi. It localises to the cytosol and nucleus. Phenotypic associations include autophagy, powdery mildew resistance, cell death, protein degradation, resistance to necrotrophic fungal pathogens and Botrytis cinerea, disease resistance, and peroxisome degradation. Studies of related genes in other species link the family to nutrient stress tolerance, salt tolerance, oxidative stress tolerance, pexophagy, hydrotropic response, and senescence. Sequence similarity connections further associate the family with harvest index, drought tolerance, and disease tolerance traits.