MSH2 — Brassica oleracea var. botrytis

Summary

BoMSH2, the cauliflower MSH2 gene on chromosome 2, encodes a DNA mismatch repair protein belonging to the MutS family, with domains including Msh2_ATP-bd and DNA_mismatch_repair_Msh2. The product exhibits mispair binding, ATP-dependent DNA damage sensor activity, damaged DNA binding, and ATP binding, and localises to the nucleus, chromosome, and plasmalemma. It is associated with mismatch repair, suppression of meiotic recombination, homologous chromosome segregation, chiasma assembly, and resolution of meiotic recombination intermediates. Traits linked to this gene include inflorescence number, fruit position, silique morphology, UV-B light sensitivity, days to flowering, lateral root length, stomatal closure time, and salt tolerance. Phenotypes connected include meiotic recombination, salt stress response, germination rate, root elongation, and cell cycle regulation. Related genes in other species link the family to DNA mismatch repair, genomic stability, homologous recombination, and meiotic crossover formation.