HAC1 — Brassica oleracea var. botrytis

Summary

BoHAC1, on cauliflower chromosome 2, encodes a protein with histone acetylase activity, chromatin DNA binding, transcription coactivator activity, and protein dimerization activity, containing CBP/p300 and multiple zinc-finger domains. It is associated with protein acetylation, positive regulation of transcription by RNA polymerase II, and photoperiodism, flowering. The gene has been connected to guard cell fate commitment, guard mother cell differentiation, and guard cell differentiation, as well as response to low humidity. Associations include arsenic accumulation and tolerance, arsenite efflux, arsenic translocation, bacterial resistance, herbivore defense, leaf senescence, root development, floral development, hypocotyl elongation, oxidative stress tolerance, starch degradation, shoot regeneration, and plant size. It localises to the nucleus, transcription regulator complex, histone acetylase complex, and mediator complex. Studies of related genes in other species link the family to root-to-shoot arsenic translocation, flowering time, thermotolerance, and stomatal development.