PI3K — Brassica oleracea

Summary

BoPI3K, located on chromosome 9 of cabbage (Brassica oleracea), encodes a phosphatidylinositol 3-kinase of the Vps34 class III type, containing PI3K catalytic and accessory domains and a C2 domain. The gene is associated with phosphatidylinositol 3-phosphate biosynthesis, macroautophagy, pexophagy, TOR signaling, endocytosis, secretion, the MAPK cascade, and activation of defence response to bacteria. It has been linked to regulation of stomatal closure, response to salt, reactive oxygen species metabolism, microgametogenesis, and fat cell differentiation. The encoded protein is associated with the class III PI3K complex, endosome and Golgi membranes, the TOR complex, and the PAS. Associations with leaf senescence, pollen development and germination, root hair growth, proline accumulation, and heat stress recovery have been noted. Studies of related genes in other species link the family to plant growth and development, disease resistance, and stomatal closure.