FLS2 — Brassica oleracea

Summary

BoFLS2, located on cabbage chromosome 9, encodes a transmembrane receptor protein serine/threonine kinase with leucine-rich repeat domains and additional annotated activities including protein kinase binding, calmodulin binding, and nucleotide binding. This gene is associated with detection of bacteria, pattern recognition receptor signaling, regulation of defense responses to bacteria, and both upregulation and downregulation of immune responses, including systemic acquired resistance and antiviral responses. It is linked to salicylic acid signaling, calcium ion homeostasis, and anti-apoptosis. BoFLS2 has been connected to numerous agronomically relevant traits such as bacterial disease resistance, drought stress tolerance, chilling tolerance, biomass yield, plant height, flowering time, leaf morphology, root hair length, anthocyanin content, and responses to aphids, aluminum, high temperature, and water stress. Related genes in other species are linked to flagellin perception, pathogen recognition, and broad-spectrum disease resistance.