TOPP1 — Brassica oleracea

Summary

BoTOPP1, encoded by gene BOLC102_C04P022260.1 on chromosome 4 of cabbage (Brassica oleracea), is a protein serine/threonine phosphatase belonging to the PP1-like family, with domains including STPPase_N and calcineurin-like PHP. The product exhibits protein serine/threonine phosphatase activity and protein phosphatase inhibitor activity, and binds metals. It is associated with protein dephosphorylation, ABA signaling, and salt tolerance, and is linked to post-transcriptional gene silencing, microsporogenesis, and embryo development ending in seed dormancy. The protein localizes to the cytoplasm, nucleus, and protein phosphatase type 1 complex. Studies of related genes in other species connect the family to cell cycle control, disease resistance, and abscisic acid sensitivity, though these associations are not yet established in cabbage.