GSM1 — Brassica oleracea

Summary

BoGSM1 (BOLC102_C02P068170.1_BOLC102_V1) on cabbage chromosome 2 encodes a protein with methylthioalkylmalate synthase and 2-isopropylmalate synthase activities, belonging to the AIPM/Hcit_synth_CS and related domain families. The gene is associated with glucosinolate biosynthesis and metabolism, including aliphatic glucosinolate side-chain length and composition, as well as L-leucine biosynthesis and anabolism. It is linked to response to insect, leaf development, stem thickness, leaf width, nodulation, and response to thirst. The encoded protein localises to the chloroplast (GO:0009507). Studies of related genes in other species connect the family to 2-isopropylmalate synthase activity (EC 2.3.3.13) and altered glucosinolate composition, though these functions are not established for BoGSM1 itself.