MIEL1 — Brassica oleracea

Summary

BoMIEL1 (BOLC102_C03P011010.1) on cabbage chromosome 3 encodes a RING-type zinc-finger protein with ubiquitin ligase activity and transcription factor binding capacity. The gene is associated with protein ubiquitination and the upregulation of proteasomal ubiquitin-dependent protein catabolic processes. It has been linked to glucose-mediated signaling, inhibition of defence responses to bacteria, wax and anthocyanin biosynthesis, and response to thirst. Associations include leaf color, proline content, drought tolerance, seed germination, cuticular wax biosynthesis, auxin metabolism, lipid droplet mobilization, abscisic acid signaling, and biotic stress response. The protein localizes to both the cytoplasm and nucleus. Studies of related genes in other species connect the family to auxin content, root length, seed development, and abscisic acid sensitivity.