CYP81F1 — Brassica oleracea

Summary

BoCYP81F1 (CYP81F1) on cabbage chromosome 1 encodes a cytochrome P450 monooxygenase with isoflavone 2'-hydroxylase, piperitol synthase, and 4'-methoxyisoflavone 2'-hydroxylase activities, binding heme and iron. It is associated with indole glucosinolate metabolism and glucosinolate anabolism, as well as seed germination. The protein localises to the endoplasmic reticulum membrane and is also linked to mitochondria. Camalexin accumulation has been observed in connection with this gene. Studies of related genes in other species link the family to cytoplasmic male sterility and heterosis, though these associations are not established for cabbage.