HMA2 — Brassica napus

Summary

BnHMA2 (DARMORV10_C01P08990.1) on oilseed rape chromosome C01 encodes a P-type ATPase of the IB subfamily, with copper, zinc, cadmium and calcium transporter activities, copper binding and ATP hydrolase activity. The gene is associated with detoxification of copper ions, copper and zinc ion homeostasis, proton export across the plasma membrane, cell pH regulation, and response to toxic substances. It localises to the vacuolar, Golgi and plasma membranes. BnHMA2 is linked to photosynthetic rate, germination rate, stomatal resistance, and to cadmium tolerance, translocation and accumulation, zinc partitioning and transport, metal homeostasis, and fungal resistance. Related genes in other species are linked to cadmium xylem loading, long-distance cadmium translocation, and zinc homeostasis.