IRT1 — Brassica napus

Summary

BnIRT1 (DARMORV10_C01P13700.1) on chromosome C01 of oilseed rape (Brassica napus) encodes a member of the ZIP family of metal transporters, possessing iron, zinc, manganese, copper and cadmium ion transmembrane transporter activities. The gene is associated with metal homeostasis, including iron, zinc and cadmium accumulation and transport, as well as responses to iron deficiency and chromium stress. It is linked to photosynthetic rate, chlorophyll content, leaf chlorosis, stomatal resistance, germination rate, root and leaf development, and plant growth traits. Additional associations include pollen germination, cellular response to hypoxia, response to bacteria, and regulation of abscisic acid-mediated signalling. The encoded protein localises to the plasmalemma, endosome, late endosome membrane and ESCRT I complex, and is linked to MVB formation and endosome membrane budding. Studies of related genes in other species connect the family to iron acquisition, nickel accumulation and cadmium sensitivity.