HMA2 — Brassica napus

Summary

BnHMA2 (HMA2) on chromosome A01 of oilseed rape encodes a P-type ATPase of the IB subfamily, annotated with divalent copper, monovalent copper, zinc, cadmium and calcium transporter activities, copper binding, calmodulin binding and ATP hydrolase activity. The gene is associated with detoxification of copper ions, copper and zinc ion homeostasis, response to toxic substances, pollen germination, membrane transport, response to cold and response to thirst. It localises to the vacuolar membrane, Golgi membrane and plasmalemma. Associations with photosynthetic rate, germination rate, stomatal resistance, zinc partitioning, cadmium tolerance and translocation, metal homeostasis, fungal resistance, cadmium accumulation and sensitivity have been reported. Studies of related genes in other species link the HMA2 family to zinc homeostasis, cadmium xylem loading and long-distance translocation.