PPAR — Brassica juncea

Summary

BJUB02G06210S (symbol PPAR) on Indian mustard chromosome B02 encodes a protein with a D-isomer-specific 2-hydroxyacid dehydrogenase catalytic domain and a basic helix-loop-helix (bHLH) domain, conferring both DNA-binding transcription factor activity and multiple oxidoreductase activities including (2R)-hydroxyphenylpyruvate reductase, hydroxypyruvate reductase, glyoxylate reductase, and D-lactate dehydrogenase activities. This gene is associated with photorespiration, lipogenesis, fatty acid oxidation, fat cell differentiation, heat generation, angiogenesis, myelination, regeneration, and regulation of transcription. The encoded protein localises to both the cytosol and nucleus. Studies of related genes in other species link the family to additional oxidoreductase activities (EC 1.1.1.237, 1.1.1.110, 1.1.1.26, 1.1.1.28, 1.1.1.79).