PPAR — Brassica juncea

Summary

BJUB02G06230S, designated PPAR, is a gene on chromosome B02 of Indian mustard (Brassica juncea). It encodes a protein containing a D-isomer-specific 2-hydroxyacid dehydrogenase catalytic domain and exhibits multiple NAD(P)H-dependent reductase activities, including (2R)-hydroxyphenylpyruvate reductase, hydroxypyruvate reductase, glyoxylate reductase, and D-lactate dehydrogenase activity. The product is localised to the cytosol. PPAR is associated with photorespiration, fatty acid oxidation, lipogenesis, fat cell differentiation, heat generation, angiogenesis, myelination, and regeneration. Studies of related genes in other species link the family to hydroxypyruvate reductase (EC 1.1.1.237) and glyoxylate reductase (EC 1.1.1.26) activities.