ERD8 — Brachypodium distachyon

Summary

BdERD8 (ERD8, HSP81.4) on Brachypodium distachyon chromosome 3 encodes a member of the heat shock protein 90 (Hsp90) family, characterized by Hsp90_N, Hsp90_C, and HATPase domains, and is annotated as an ATP-dependent protein folding chaperone with additional annotated activities including transcription regulator activity, siRNA and miRNA binding, RNA endonuclease activity, and ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase. The gene is associated with diverse biological processes such as chaperone-mediated protein complex assembly, protein stabilization, cellular response to brassinosteroid stimulus, auxin metabolism, root hair cell differentiation, leaf proximal/distal pattern formation, and photoentrainment of the circadian clock. It is linked to traits including maturity time, photoperiod-sensitive flowering, reproductive growth time, seed viability, starch grain synthesis, shoot meristem development, inflorescence morphology, and responses to viral disease, aphids, downy mildew, and zinc sensitivity. Localization evidence connects the protein to the chloroplast outer membrane, ER lumen, vesicle, and proteasome.